Biologic Infusions for Rheumatoid Arthritis: A Patient's Guide

When other medicines aren't controlling rheumatoid arthritis, your rheumatologist may suggest a biologic infusion. Here's what to know.

Care provider holding a patient's hands, a moment of trust and reassurance

Rheumatoid arthritis (RA) is an autoimmune condition in which the immune system attacks the lining of the joints, causing pain, swelling and stiffness. Over time, uncontrolled inflammation can damage joints. There are more treatment options today than ever, and for many people, biologic infusions are part of the plan.

Where infusions fit in RA treatment

RA treatment usually starts with disease-modifying medicines taken by mouth or injection, such as methotrexate. If those don't control inflammation well enough, or cause side effects, a rheumatologist may add or switch to a biologic or another targeted therapy. Some of these are given as IV infusions.

Infused biologics used for RA

  • Infliximab (Remicade and biosimilars such as Avsola, Inflectra and Renflexis)
  • Simponi Aria (golimumab)
  • Orencia (abatacept)
  • Actemra (tocilizumab)
  • Rituxan (rituximab) and its biosimilars

These medicines work in different ways. Some block TNF, a protein that drives inflammation; others target different parts of the immune response. Your rheumatologist chooses based on your history, other health conditions and insurance coverage.

How often will I need an infusion?

It depends on the medicine. Many start with a few starting doses closer together, then settle into a maintenance schedule that may range from every four weeks to every eight weeks, or longer for some therapies. Infusion times vary too, from under an hour to several hours. Your care team will give you a clear schedule.

What results can I expect?

Biologics don't cure RA, but they may help reduce pain, swelling and stiffness and slow joint damage. Some people notice improvement within weeks; for others it takes a few months. Your rheumatologist will track how you're doing and adjust the plan if needed.

Safety and screening

Because biologics affect the immune system, they can raise the risk of infection. Before starting, you'll usually be screened for tuberculosis and hepatitis B. During treatment, tell your care team if you have a fever, an infection or a planned surgery, and ask before getting any live vaccines. Infusion reactions can occur, which is why nurses monitor you during every visit.

RA infusions in Toms River, NJ

Infuse Care gives rheumatologist-prescribed infusions in private suites, with nurses who monitor each treatment and send updates to your rheumatologist. Learn more about rheumatoid arthritis and our rheumatology services, or call 732-444-8808 to get started.

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Rheumatology

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This article is general information, not medical advice. Your doctor can help you decide what's right for your situation.

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